U.S. and Chinese scientists are working together to study the effects of the Corydalis plant, which has been used for thousands of years in traditional Chinese medicine to relieve pain.
The Journal of Current Biology reported a study done on mice that showed promising effects of dehydrocorybulbine (DHCB), one of many active compounds found in the underground tubers of the Corydalis plants. DHCB was found to effectively alleviate three types of pain via 2D dopamine receptors: temporary acute, inflammatory, and chronic pain. In addition, it was observed that the mice did not build up a resistance to the naturally occurring compound. This study suggests that the compound can be used to help manage chronic pain in humans. Dr. Olivier Crivellia, a pharmacologist at UC Irvine and one of the authors of the study, stated that “there are likely many compounds inside [the] plants that have some effects on a particular disease or disorder” and that “[their] goal is to find the most powerful [one] of those compounds.”
Click here to read the full article in the Los Angeles Times Science Section, January 4th, 2014.